ISC High Performance 2026 is the 40th anniversary of the world's leading forum for advancing the application of high performance computing in academia, government, and the private sector. The event takes place in Hamburg, Germany from June 22-26, 2026. The goal of ISC 2026 is to foster a global exchange of knowledge, innovation, and collaboration in the field of high performance computing, AI, and quantum technologies. The event connects scientists, engineers, and technology leaders to explore the future of high performance computing, examine today's breakthroughs, and discuss what lies ahead. ISC 2026 is committed to sustainability by promoting energy-efficient and cost-effective computing, while empowering the next-generation workforce to continue the community's legacy of innovation. The event features keynote speakers, including Martin Schulz, Amanda Randles, and Jack Dongarra, who will discuss the latest advancements in the field. The program also includes speaker spotlights, a community stage for sparking debates and sharing ideas, and contributed program submissions, including research papers, posters, and workshops. The exhibition brings together over 200 leading organizations from industry, research, and academia, offering a unique picture of the converging ecosystems of HPC, AI, and quantum technologies. The event provides opportunities for networking and social activities, with nearly 50% of HPC users, vendors, and providers participating exclusively at ISC. With a comprehensive program addressing HPC and AI innovation, insights from 800+ speakers, and a unique format that bridges technology and community, ISC 2026 is a must-attend event for anyone interested in the latest developments in high performance computing.